By Charles P. Ordahl
ISBN-10: 0080494382
ISBN-13: 9780080494388
ISBN-10: 0121531481
ISBN-13: 9780121531485
The chapters contained during this two-volume set supply a huge viewpoint at the novel suggestions and conceptual paradigms that force the present resurgence of curiosity in somitogenesis - the method in which somites shape and complex differentiated tissues and buildings. simply because somites are a ubiquitous characteristic of vertebrate embryos, they are often studied in numerous experimental animal types together with these amenable to genetic (zebrafish, mammalian), molecular/genetic (mammalian, avian) in addition to these already good tested for classical experimental embryological and mobile organic reviews (amphibians, avian). the big variety of experimental techniques to somitogenesis which are offered in those volumes will go away the reader with a extensive point of view on how present examine in somitogenesis helps to unravel basic questions in vertebrate improvement and morphogenesis. Key good points* Novel transcriptional mechanisms that keep watch over repetitive trend formation* Wide-scale genetic monitors for mutations affecting somitogenesis* Molecular/genetic keep watch over of trend and tissue formation in the course of somitogenesis* Transplantation of mouse embryo somites* Classical embryological ways and ideas* Evolutionary views on somitogenesis
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Somitogenesis: Part 2 by Charles P. Ordahl PDF
The chapters contained during this two-volume set offer a large standpoint at the novel suggestions and conceptual paradigms that force the present resurgence of curiosity in somitogenesis - the method during which somites shape and problematic differentiated tissues and buildings. simply because somites are a ubiquitous function of vertebrate embryos, they are often studied in a number of experimental animal types together with these amenable to genetic (zebrafish, mammalian), molecular/genetic (mammalian, avian) in addition to these already good confirmed for classical experimental embryological and mobile organic reviews (amphibians, avian).
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178, 160 –173. , Müller T. , and Birchmeier, C. (1996b). Scatter factor/ hepatocyte growth factor (SF/HGF) induces emigration of myogenic cells at interlimb level in vivo. Dev. Biol. 179, 303 –308. , Barde, Y. , and Kalcheim, C. (1995). Epithelial– mesenchymal conversion of dermatome progenitors requires neural tube-derived signals: Characterization of the role of Neurotrophin-3. Development 121, 2583 –2594. , and Stockdale, F. E. (1994). Myogenic specification in somites: Induction by axial structures.
178, 403 – 417. 42 Beate Brand-Saberi and Bodo Christ Münsterberg, A. , and Lassar, A. B. (1995). Combinatorial signals from the neural tube, floor plate and notochord induce myogenic bHLH gene expression in the somite. Development 121, 651– 660. Münsterberg, A. , Bumcrot, D. , McMahon, A. , and Lassar, A. B. (1995). Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite. Genes Dev. 9, 2911–2922. Olson, E. , Perry, W. , and Schulz, R.
These comparative data show that neural arch elements can be found earlier than central ones during evolution and that both axial or central structures can be traced back to two skeletal elements, the pleurocentrum and the hypocentrum. It has been shown that genes such as hairy and engrailed that are involved in segmentation of Drosophila are also expressed before and during somite formation in Amphioxus and zebrafish (M. , 1997). , 1995). This mode of segment formation may represent a more primitive mechanism.
Somitogenesis: Part 2 by Charles P. Ordahl
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