Download PDF by Chareeporn Akekawatchai, Marina Kochetkova, Jane Holland: Chemokine Receptors in Cancer

By Chareeporn Akekawatchai, Marina Kochetkova, Jane Holland (auth.), Amy M. Fulton (eds.)

ISBN-10: 1603272666

ISBN-13: 9781603272667

Chemokine Receptors in melanoma summarizes the becoming physique of proof that a number of chemokine receptors give a contribution to tumor habit. Chemokine receptors have been first pointed out on leukocytes and mediate directed migration of many host cells to websites of ligand expression. it's now good verified that the majority malignant cells additionally exhibit a number of chemokine receptor. This e-book describes our present realizing relating to how chemokine receptors give a contribution to tumor cellphone migration in addition to cellphone survival and proliferation. The functionality of chemokine receptors expressed on host cells together with antitumor immune effector cells in addition to angiostatic and angiogeneic capabilities of chemokines performing on endothelial cells are defined. The function of chemokine receptors that act as decoy receptors is additionally summarized. The healing strength and demanding situations of focusing on chemokine receptors or cognate ligands can be addressed.

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Chemokine Receptors in melanoma summarizes the turning out to be physique of proof that a number of chemokine receptors give a contribution to tumor habit. Chemokine receptors have been first pointed out on leukocytes and mediate directed migration of many host cells to websites of ligand expression. it's now good tested that the majority malignant cells additionally convey a number of chemokine receptor.

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Hsiao Y. , Chen Y. , et al. (2007) Stromal cell-derived factor-1 enhances motility and integrin up-regulation through CXCR4, ERK and NF-kappaB-dependent pathway in human lung cancer cells. , 74, 1702–12. 75. Phillips R. , Burdick M. , et al. (2003). The stromal derived factor-1/ CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases. , 167, 1676–86. 76. , et al.. (2004) Stromal-derived factor1alpha/CXCL12-CXCR 4 axis is involved in the dissemination of NSCLC cells into pleural space.

Urology 53(1): 139–47. 128. , et al. (2005). Breast cancer. Lancet 365(9472): 1727–41. 129. Vicari, A. P. and Caux, C. (2002). "Chemokines in cancer. Cytokine Growth Factor Rev 13(2): 143–54. 130. Walden, P. , et al. (1998). Evidence that the mammary fat pad mediates the action of growth hormone in mammary gland development. Endocrinology 139(2): 659–62. 131. , et al. (2004). The role of G-protein coupled receptors and associated proteins in receptor tyrosine kinase signal transduction. Semin Cell Dev Biol 15(3): 309–23.

15. Baserga (1995) 16. , Peruzzi, F. et al. (2003). The IGF-1 receptor in cancer biology. Int J Cancer 107(6): 873–7. 17. , Fantini, M. , et al. (2004). TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling. Immunity 21(4): 491–501. 18. ,. Noonan, D. , et al. (2002). Tumors and inflammatory infiltrates: friends or foes? Clin Exp Metastasis 19(3): 247–58. 19. , Burger, J. , et al. (1999). Point mutation causing constitutive signaling of CXCR2 leads to transforming activity similar to Kaposi’s sarcoma herpesvirus-G protein-coupled receptor.

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Chemokine Receptors in Cancer by Chareeporn Akekawatchai, Marina Kochetkova, Jane Holland (auth.), Amy M. Fulton (eds.)


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