By Chareeporn Akekawatchai, Marina Kochetkova, Jane Holland (auth.), Amy M. Fulton (eds.)
Chemokine Receptors in melanoma summarizes the becoming physique of proof that a number of chemokine receptors give a contribution to tumor habit. Chemokine receptors have been first pointed out on leukocytes and mediate directed migration of many host cells to websites of ligand expression. it's now good verified that the majority malignant cells additionally exhibit a number of chemokine receptor. This e-book describes our present realizing relating to how chemokine receptors give a contribution to tumor cellphone migration in addition to cellphone survival and proliferation. The functionality of chemokine receptors expressed on host cells together with antitumor immune effector cells in addition to angiostatic and angiogeneic capabilities of chemokines performing on endothelial cells are defined. The function of chemokine receptors that act as decoy receptors is additionally summarized. The healing strength and demanding situations of focusing on chemokine receptors or cognate ligands can be addressed.
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Chemokine Receptors in melanoma summarizes the turning out to be physique of proof that a number of chemokine receptors give a contribution to tumor habit. Chemokine receptors have been first pointed out on leukocytes and mediate directed migration of many host cells to websites of ligand expression. it's now good tested that the majority malignant cells additionally convey a number of chemokine receptor.
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Additional info for Chemokine Receptors in Cancer
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Chemokine Receptors in Cancer by Chareeporn Akekawatchai, Marina Kochetkova, Jane Holland (auth.), Amy M. Fulton (eds.)