Download e-book for kindle: Anti-aging in Ophthalmology: Special Issue: Ophthalmic by K. Tsubota

By K. Tsubota

ISBN-10: 3805595743

ISBN-13: 9783805595742

The various ailments resulting in blindness comparable to cataract, glaucoma, diabetic retinopathy and age-related macular degeneration correlate with the patient's age. Even genetic issues resembling retinitis pigmentosa might be thought of 'premature getting older of the retina', and extra, dry eye or presbyopia, which may dramatically impact caliber of imaginative and prescient, are age similar. Antiaging study turns into an increasing number of vital nowadays, even supposing the basics aren't but basic usual within the hospital; besides the fact that, reactive oxygen species regulate looks the start. sooner or later, a formal vitamin, together with calorie restrict or antioxidant meals elements, antioxidant vitamins, workout in addition to drug intervention could play an essential function within the fight opposed to age-related eye issues. This quantity indicates the newest advancements and should be a useful replace with regards to age-related eye illnesses not just for ophthalmologists, but in addition for basic physicians.

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Extra info for Anti-aging in Ophthalmology: Special Issue: Ophthalmic Research 2010, Vol. 44, No. 3

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38 Morrison JC, et al: Structural proteins of the neonatal and adult lamina cribrosa. Arch Ophthalmol 1989; 107:1220–1224. 39 Albon J, et al: Age related changes in the noncollagenous components of the extracellular matrix of the human lamina cribrosa. Br J Ophthalmol 2000;84:311–317. 40 Burgoyne CF, Downs JC: Premise and prediction: how optic nerve head biomechanics underlies the susceptibility and clinical behavior of the aged optic nerve head. J Glaucoma 2008;17:318–328. 41 Yang H, et al: 3-D histomorphometry of the normal and early glaucomatous monkey optic nerve head: lamina cribrosa and peripapillary scleral position and thickness.

Insight 2004;29:15–16. 46 Veach J: Functional dichotomy: glutathione and vitamin E in homeostasis relevant to primary open-angle glaucoma. Br J Nutr 2004; 91:809–829. 47 Klein BE, Knudtson MD, Lee KE, Reinke JO, Danforth LG, Wealti AM, Moore E, Klein R: Supplements and age-related eye conditions: the Beaver Dam Eye Study. Ophthalmology 2008;115:1203–1208. 48 Acar N, Berdeaux O, Juaneda P, Grégoire S, Cabaret S, Joffre C, Creuzot-Garcher CP, Bretillon L, Bron AM: Red blood cell plasmalogens and docosahexaenoic acid are independently reduced in primary open-angle glaucoma.

G. g. age-related macular degeneration, cataract and diabetic retinopathy). Mitochondrial DNA (mtDNA) instability is an important factor in mitochondrial impairment culminating in age-related changes and pathology, and in all regions of the eye mtDNA damage is increased as a consequence of aging and age-related disease. It is now apparent that the mitochondrial genome is a weak link in the defenses of ocular cells since it is susceptible to oxidative damage and it lacks some of the systems that protect the nuclear genome, such as nucleotide excision repair.

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Anti-aging in Ophthalmology: Special Issue: Ophthalmic Research 2010, Vol. 44, No. 3 by K. Tsubota

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